Description

English | 2018 | PDF | 9 MB | 206 Pages

Leonard Guarente, Raul Mostoslavsky, Aleksey Kazantsev, B07CP46HWL, 0128134992, 012813500X, 9780128134993, 978-0128134993, 978-0-12-813499-3, 9780128135006, 978-0128135006
Introductory Review on Sirtuins in Biology and Disease provides key insights for scientists and advanced students who need to understand sirtuins and the current research in this field. This book is ideal for pharmaceutical companies as they develop novel targets using sirtuins for metabolic diseases, cancer and neurodegenerative illnesses. Sirtuins are a diverse family of proteins, with several members in mammals. The functional diversity of sirtuins is rather broad, and they have been implicated in various central biological processes. Thus, they are also highly relevant in the context of various human diseases, from cancer to neurodegeneration.

Covers both the general and specific aspects of sirtuin proteins and their role in biology, aging and disease
Presents a top quality collection of leading experts who contribute on a wide range of sirtuin-related topics
Ideal resource for pharmaceutical companies as they develop novel targets using sirtuins for metabolic diseases, cancer and neurodegenerative illnesses