Single best answer multiple choice questions are considered invaluable in assessing a trainee’s ability to apply knowledge to clinical practice. This book comprises six sets of practice papers, each set containing 30 single best answer questions in basic sciences applicable to the practice of anaesthesia, pain management and intensive care. The single best answer stem is presented as a clinical problem followed by a lead-in question and five possible options. The best possible answer to a given question is substantiated by detailed explanation drawn from recent review articles and textbooks in anaesthesia and basic sciences. At the end of the answer section to each question, a useful list of references are provided to aid further reading. These questions will enable candidates to assess how well they can apply their factual knowledge on basic sciences to their clinical practice. Alongside the authors’ previously published book, “Single Best Answer MCQs in Anaesthesia: Volume 1 – Clinical Anaesthesia”, this book supplements the essential study material for post-graduate examinations in anaesthesia and intensive care medicine. This book is also a valuable educational resource for all trainees and practicing anaesthetists.